Part1.What is Macleaya cordata extract？
Macleaya cordata extract is an orange-yellow powder processed from the fruit of Papaveraceae Boluohui. It contains sanguinarine and chelerythrine in a total amount of not less than 60.0%. It has antibacterial, anti-inflammatory, appetizing and promoting Growth effect, mainly used to promote the growth of pigs and chickens. Macleayacordata is a plant of the family Poppyaceae, commonly known as Tonggan, Shanjiao, and Luohui. It has been used as a medicine in China for more than a thousand years. It is a whole plant with roots that is pungent, bitter, warm in nature, and highly toxic. , detumescence, parasite killing, mainly cures furunculosis abscess, malignant sore ulcer, scald, scabies etc.
Modern pharmacological studies have shown that the main active ingredient of Boluohui is alkaloids, which have the functions of antibacterial, antitumor, detumescence, killing insects and maggots, relieving cough and asthma, and improving liver function. Folks are mainly used for the treatment of boils and carbuncles, trichomonas vaginalis, bruises, athlete's foot, eczema, etc. Modern studies have shown that the alkaloids in Boluohui have good antiviral hepatitis and other effects.
Part2: Pharmacological effects
1. Antibacterial effect
The water decoction of this product has a strong inhibitory effect on a variety of Gram-positive and negative bacteria and Leptospira. It has been reported that the "horn injection" prepared from Boluoboluohui whole leather has a strong inhibitory effect on Staphylococcus aureus, P. albicans, Staphylococcus albus, and Shigella flexneri. The antibacterial active ingredients of this product are alkaloids, and ethoxysanguinarine also has a strong killing effect on Leptospira in vitro.
2. Insecticidal effect
Macleaya cordata extract has a powerful effect of killing trichomonas vaginalis. When trichomonas is contacted with Boluohui extract on a glass slide, all trichomonas will be killed immediately.
3. The effect of killing maggots
Macleaya cordata extract is a commonly used herbal medicine for killing maggots among the people. It can make fly maggots excited first, then paralyze and die, and can inhibit the hatching of fly eggs. The maggot-killing effect is strongest in leaves and fruit peels, followed by stems, and the weakest in roots. The ability to kill maggots is not lost due to drying. The active ingredient for killing maggots is alkaloid.
4. Anti-tumor effect
The two active ingredients of Macleaya cordata extract have the ability to induce the human telomere DNA to form a G-quadruplex structure, thereby inhibiting the activity of telomerase and inhibiting the proliferation of tumor cells.
5. Other functions
The sulfate of Macleaya cordata extract total alkaloids has a local anesthetic effect, which is similar to that of procaine hydrochloride.
